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Acute Ischemic Stroke

Acute Ischemic Stroke

Acute ischemic stroke occurs when the blood supply to certain parts of the brain is suddenly cut off, leading to a loss of cognitive functioning (Phipps & Cronin, 2020). The trigger to loss of supply is blockage of the cerebral vessel that supplies blood to that affected area of the brain. Several physiological processes and elements are involved during acute ischemic s

troke. One of the elements that play an important role in ischemic stroke is blood glucose. Blood glucose is essential for the brain because it is essential for the survival of brain cells together with oxygen (Maida et al., 2022). Inadequate glucose supply to the brain worsens the outcome of acute ischemic stroke because the brain would not have sufficient energy to function properly, causing further damage to the brain cells.

Similarly, high blood glucose levels in the body can also contribute to events that lead to acute ischemic stroke. For instance, hyperglycemia, which is characterized by uncontrolled and elevated blood glucose levels causes functional and structural changes to the vessels that carry blood to and from the heart (Maida et al., 2022). An example of structural changes is the narrowing of the blood vessels, leading to reduced blood flow. Hence, the heart has to work extra hard to compensate for the insufficient blood supply, causing hypertension. As the blood pressure continues to elevate, it damages the arteries, increasing the risk of clot formation. The presence of blood clots in the arteries can cut blood supply to the vessels supplying the brain, causing a stroke. Hence, the relationship between blood glucose and acute ischemic stroke is characterized by high blood pressure that causes impairment in the blood supply to the brain. As evidence of the relationship, patients who experience stroke and have hyperglycemia have an increased risk of hemorrhage, large infarct size, and increased risk of mortality (Mosenzon et al., 2023).

 

References

Maida, C., Daidone, M., Pacinella, G., Norrito, R., & Pinto, A. (2022). Tuttolomondo A. Diabetes and Ischemic Stroke: An Old and New Relationship:An Overview of the Close Interaction between These Diseases. International Journal of Molecular Sciences, 23(4):2397. https://doi.org/10.3390/ijms23042397.

Mosenzon, O., Cheng, A., Rabinstein, A., & Sacco, S. (2023). Diabetes and Stroke: What Are the Connections? Journal of Stroke, 25(1):26-38. https://doi.10.5853/jos.2022.02306.

Phipps, M. S., & Cronin, C. (2020). Management of acute ischemic stroke. BMJ, 368. https://doi.org/10.1136/bmj.l6983.

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Topic 1: Differentiating Quality Improvement, Evidence-Based Practice, And Research

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Describe at least two limitations to both primary and secondary data and how understanding those limitations can improve your future CQI work

What is the difference between primary and secondary data?

Choose the two elements that you feel are the most difficult to achieve and provide one strategy for each that will make them achievable.

What two elements do you believe play the most significant role in sustaining change and why?

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It is important to ensure that a candidate fits into the culture of the organization.

What formal and informal onboarding or assimilation processes exist in your organization or an organization with which you are familiar?

What do you think is most necessary for learning to occur in your current organization?

Click here to ORDER an A++ paper from our Verified MASTERS and DOCTORATE WRITERS: Acute Ischemic Stroke

Thank you JA for your in-depth and concise discussion about the concepts of statistical significance of research findings and clinical significance of such evidence. I agree with you based on your assertions that nurses, especially those with limited experience in research, should be cautious on their interpretation of statistical significance and clinical significance of their research findings. Accordingly, healthcare providers and researcher interpret statistically significant results as clinically important (Armijo-Olivo, 2018). The statistical significance shows the level of reliability of the study outcomes but clinical significance illustrates the importance of the results in clinical practice and provision of care interventions.

In broadly terms, statistical significance implies that such findings are likely to happen while clinical significance determines the level of impact. Sharma (2021) opines that clinical significance looks at the differences between the two groups while clinical significance looks at the similarities and how providers can leverage them to develop clinical interventions to improve patient and population health. clinical significance seeks to comprehend the extent and scope of an effects and is essential for decision makers in diverse industries, especially those in pharmaceuticals and psychological research studies. The implication is that one must always consider the different aspects of these two phenomena in their research to attain the most effective outcomes (Ranganathan et al., 2019). Subjective evaluation can have negative effects on the outcomes and it is essential for nurse research to consider all aspects associated with the two approaches in getting the significance of either results. I agree with you that one can use clinical significance to attain positive outcomes by ensuring that the outcomes are statistically relevant to the aspects under investigations.

 

References

Armijo-Olivo, S. (2018). The importance of determining the clinical significance of research

results in physical therapy clinical research. Brazilian journal of physical therapy, 22(3), 175. DOI: 10.1016/j.bjpt.2018.02.001

Ranganathan, P., Pramesh, C. S., & Buyse, M. (2019). Common pitfalls in statistical analysis:

Clinical versus statistical significance. Perspectives in clinical research, 6(3), 169. DOI: 10.4103/2229-3485.159943

Sharma, H. (2021). Statistical significance or clinical significance? A researcher’s dilemma for

appropriate interpretation of research results. Saudi Journal of Anesthesia, 15(4), 431. DOI: 10.4103/sja.sja_158_21.

Lopes Write Policy

For assignments that need to be submitted to Lopes Write, please be sure you have received your report and Similarity Index (SI) percentage BEFORE you do a “final submit” to me.

Once you have received your report, please review it. This report will show you grammatical, punctuation, and spelling errors that can easily be fixed. Take the extra few minutes to review instead of getting counted off for these mistakes.

Review your similarities. Did you forget to cite something? Did you not paraphrase well enough? Is your paper made up of someone else’s thoughts more than your own?

Visit the Writing Center in the Student Success Center, under the Resources tab in LoudCloud for tips on improving your paper and SI score.

Late Policy

The university’s policy on late assignments is 10% penalty PER DAY LATE. This also applies to late DQ replies.

Please communicate with me if you anticipate having to submit an assignment late. I am happy to be flexible, with advance notice. We may be able to work out an extension based on extenuating circumstances.

If you do not communicate with me before submitting an assignment late, the GCU late policy will be in effect.

I do not accept assignments that are two or more weeks late unless we have worked out an extension.

As per policy, no assignments are accepted after the last day of class. Any assignment submitted after midnight on the last day of class will not be accepted for grading.

Communication

Communication is so very important. There are multiple ways to communicate with me:

Questions to Instructor Forum: This is a great place to ask course content or assignment questions. If you have a question, there is a good chance one of your peers does as well. This is a public forum for the class.

Individual Forum: This is a private forum to ask me questions or send me messages. This will be checked at least once every 24 hours.

Important information for writing discussion questions and participation

Welcome to class

Hello class and welcome to the class and I will be your instructor for this course. This is a -week course and requires a lot of time commitment, organization, and a high level of dedication. Please use the class syllabus to guide you through all the assignments required for the course. I have also attached the classroom policies to this announcement to know your expectations for this course. Please review this document carefully and ask me any questions if you do. You could email me at any time or send me a message via the “message” icon in halo if you need to contact me. I check my email regularly, so you should get a response within 24 hours. If you have not heard from me within 24 hours and need to contact me urgently, please send a follow up text to

I strongly encourage that you do not wait until the very last minute to complete your assignments. Your assignments in weeks 4 and 5 require early planning as you would need to present a teaching plan and interview a community health provider. I advise you look at the requirements for these assignments at the beginning of the course and plan accordingly. I have posted the YouTube link that explains all the class assignments in detail. It is required that you watch this 32-minute video as the assignments from week 3 through 5 require that you follow the instructions to the letter to succeed. Failure to complete these assignments according to instructions might lead to a zero. After watching the video, please schedule a one-on-one with me to discuss your topic for your project by the second week of class. Use this link to schedule a 15-minute session. Please, call me at the time of your appointment on my number. Please note that I will NOT call you.

Please, be advised I do NOT accept any assignments by email. If you are having technical issues with uploading an assignment, contact the technical department and inform me of the issue. If you have any issues that would prevent you from getting your assignments to me by the deadline, please inform me to request a possible extension. Note that working fulltime or overtime is no excuse for late assignments. There is a 5%-point deduction for every day your assignment is late. This only applies to approved extensions. Late assignments will not be accepted.

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Plagiarism is highly prohibited. Please ensure you are citing your sources correctly using APA 7th edition. All assignments including discussion posts should be formatted in APA with the appropriate spacing, font, margin, and indents. Any papers not well formatted would be returned back to you, hence, I advise you review APA formatting style. I have attached a sample paper in APA format and will also post sample discussion responses in subsequent announcements.

Your initial discussion post should be a minimum of 200 words and response posts should be a minimum of 150 words. Be advised that I grade based on quality and not necessarily the number of words you post. A minimum of TWO references should be used for your initial post. For your response post, you do not need references as personal experiences would count as response posts. If you however cite anything from the literature for your response post, it is required that you cite your reference. You should include a minimum of THREE references for papers in this course. Please note that references should be no more than 5 years old except recommended as a resource for the class. Furthermore, for each discussion board question, you need ONE initial substantive response and TWO substantive responses to either your classmates or your instructor for a total of THREE responses. There are TWO discussion questions each week, hence, you need a total minimum of SIX discussion posts for each week. I usually post a discussion question each week. You could also respond to these as it would count towards your required SIX discussion posts for the week.

I understand this is a lot of information to cover in 5 weeks, however, the Bible says in Philippians 4:13 that we can do all things through Christ that strengthens us. Even in times like this, we are encouraged by God’s word that we have that ability in us to succeed with His strength. I pray that each and every one of you receives strength for this course and life generally as we navigate through this pandemic that is shaking our world today. Relax and enjoy the course!

Hi Class,

Please read through the following information on writing a Discussion question response and participation posts.

Contact me if you have any questions.

Important information on Writing a Discussion Question

  • Your response needs to be a minimum of 150 words (not including your list of references)
  • There needs to be at least TWO references with ONE being a peer reviewed professional journal article.
  • Include in-text citations in your response
  • Do not include quotes—instead summarize and paraphrase the information
  • Follow APA-7th edition
  • Points will be deducted if the above is not followed

Participation –replies to your classmates or instructor

  • A minimum of 6 responses per week, on at least 3 days of the week.
  • Each response needs at least ONE reference with citations—best if it is a peer reviewed journal article
  • Each response needs to be at least 75 words in length (does not include your list of references)
  • Responses need to be substantive by bringing information to the discussion or further enhance the discussion. Responses of “I agree” or “great post” does not count for the word count.
  • Follow APA 7th edition
  • Points will be deducted if the above is not followed
  • Remember to use and follow APA-7th edition for all weekly assignments, discussion questions, and participation points.
  • Here are some helpful links
  • Student paper example
  • Citing Sources
  • The Writing Center is a great resource