DNP 810 Topic 4 Discussion Question 2 PEER Posts
Grand Canyon University DNP 810 Topic 4 Discussion Question 2 PEER Posts-Step-By-Step Guide
This guide will demonstrate how to complete the DNP 810 Topic 4 Discussion Question 2 PEER Posts assignment based on general principles of academic writing. Here, we will show you the A, B, Cs of completing an academic paper, irrespective of the instructions. After guiding you through what to do, the guide will leave one or two sample essays at the end to highlight the various sections discussed below.
How to Research and Prepare for DNP 810 Topic 4 Discussion Question 2 PEER Posts
Whether one passes or fails an academic assignment such as the Grand Canyon University DNP 810 Topic 4 Discussion Question 2 PEER Posts depends on the preparation done beforehand. The first thing to do once you receive an assignment is to quickly skim through the requirements. Once that is done, start going through the instructions one by one to clearly understand what the instructor wants. The most important thing here is to understand the required format—whether it is APA, MLA, Chicago, etc.
After understanding the requirements of the paper, the next phase is to gather relevant materials. The first place to start the research process is the weekly resources. Go through the resources provided in the instructions to determine which ones fit the assignment. After reviewing the provided resources, use the university library to search for additional resources. After gathering sufficient and necessary resources, you are now ready to start drafting your paper.
How to Write the Introduction for DNP 810 Topic 4 Discussion Question 2 PEER Posts
The introduction for the Grand Canyon University DNP 810 Topic 4 Discussion Question 2 PEER Posts is where you tell the instructor what your paper will encompass. In three to four statements, highlight the important points that will form the basis of your paper. Here, you can include statistics to show the importance of the topic you will be discussing. At the end of the introduction, write a clear purpose statement outlining what exactly will be contained in the paper. This statement will start with “The purpose of this paper…” and then proceed to outline the various sections of the instructions.
How to Write the Body for DNP 810 Topic 4 Discussion Question 2 PEER Posts
After the introduction, move into the main part of the DNP 810 Topic 4 Discussion Question 2 PEER Posts assignment, which is the body. Given that the paper you will be writing is not experimental, the way you organize the headings and subheadings of your paper is critically important. In some cases, you might have to use more subheadings to properly organize the assignment. The organization will depend on the rubric provided. Carefully examine the rubric, as it will contain all the detailed requirements of the assignment. Sometimes, the rubric will have information that the normal instructions lack.
Another important factor to consider at this point is how to do citations. In-text citations are fundamental as they support the arguments and points you make in the paper. At this point, the resources gathered at the beginning will come in handy. Integrating the ideas of the authors with your own will ensure that you produce a comprehensive paper. Also, follow the given citation format. In most cases, APA 7 is the preferred format for nursing assignments.
How to Write the Conclusion for DNP 810 Topic 4 Discussion Question 2 PEER Posts
After completing the main sections, write the conclusion of your paper. The conclusion is a summary of the main points you made in your paper. However, you need to rewrite the points and not simply copy and paste them. By restating the points from each subheading, you will provide a nuanced overview of the assignment to the reader.
How to Format the References List for DNP 810 Topic 4 Discussion Question 2 PEER Posts
The very last part of your paper involves listing the sources used in your paper. These sources should be listed in alphabetical order and double-spaced. Additionally, use a hanging indent for each source that appears in this list. Lastly, only the sources cited within the body of the paper should appear here.
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DNP 810 Topic 4 Discussion Question 2 PEER Posts
Distinguish between quantitative and qualitative research. Explain why more quantitative research articles are required for support for the DPI Project as compared to qualitative research articles. Conduct a search in the GCU Library using the nursing databases for a primary quantitative article that provides support for your proposed intervention and briefly explain how the research provides evidence that the intervention would improve the problem at your practice site.
Quantitative research can be described as the research process that uses collection and numerical data analysis in research studies that generalize results to a wider population, while qualitative research uses involves collecting and analyzing non-numerical data such as interviews, questionnaires and the results are generalized for a smaller or localized population. (Bhandari, 2020). DNP 810 Topic 4 Discussion Question 2 PEER Posts
Quantitative research uses various methods for data collection, and these include experiments, observations which are recorded as numbers; and surveys/questionnaires with closed-ended questions.
Alternatively, qualitative research uses interview questions that are open-ended. Other data collection methods include observations that are described in words, literature reviews that explore concepts and reviews (Bhandari, 2020).
In quantitative research, the focus is on testing theories and developing the hypothesis, data goes through statistical analysis in numerical and graphical expressions, and requires many respondents answering closed-ended questions DNP 810 Topic 4 Discussion Question 2 PEER Posts
Qualitative research on the other hand focuses on exploration of ideas and formulation of theories or hypothesis. It is analyzed by summarizing, categorizing, and interpreting and mainly expressed in words. Qualitative research requires a few respondents and open-ended questions (Streefkerk, 2019). DNP 810 Topic 4 Discussion Question 2 PEER Posts
Quantitative research will create a major impact on my proposed DPI project because believe that this will help improve patient outcome, save cost of treatment , and provide evidence-based practice for the facility and who knows our sister facilities.
Reference DNP 810 Topic 4 Discussion Question 2 PEER Posts
Bhandari, P. (2020). What Is Quantitative Research? | Definition, Uses and …
https://www.scribbr.com/methodology/quantitative-research
Streefkerk, R. (2019). differentiate qualitative research from quantitative … – Brainly.in DNP 810 Topic 4 Discussion Question 2 PEER Posts
https://brainly.in › Science › Secondary School
Independent variables are something that can be manipulated in a research study. It is checking to see if you make changes to the study will it have the same/different effect. (Cherry 2020). For example, if you are doing a medication study giving a high dose, low dose, and placebo, you are manipulating the outcome of the study because you are controlling the outcome. DNP 810 Topic 4 Discussion Question 2 PEER Posts
A dependent variable is something that is being tested in a study, the dependent variable would be measuring blood pressures against medication use, the dependent would be blood pressure results. (Cherry 2022) The dependent and independent variable works together for example the independent would be the amount of blood pressure medications given to the person and the dependent is blood pressure results. The change comes with the manipulated variable if the patient receives a high dose of blood pressure meds the blood pressure will be lower compared to not receiving any and having no change.
The extraneous variable is any variable that is not being tested but it can affect the outcome of the study, it is uncontrolled and can lead to not valid results. (Zach 2020) for example like the other example blood pressure meds and results of blood measure, the extraneous variable would be if the participants are diets and exercising that can affect the results or if the patient is consuming extra salt, you didn’t plan on including that in your research, but it can change results if these things are happening. DNP 810 Topic 4 Discussion Question 2 PEER Posts
To controlled extraneous variables, you must know what type of study is being done. One method is random sampling which you will divide up the controlled group and experimental group by doing a random name draw. They can also do the standardized procedure which can basically equal out the environment for everyone. For example, with the blood pressure and medication study, the participants can either start diets and exercising or that can make another controlled group.
To add to what you have written, in the article by Chalmers, & Cowdell (2021), he points out that qualitative research needs to be more prevalent in health literature journals because there is a need to expound on the role of human nature and the structural contexts in the lives of individuals. DNP 810 Topic 4 Discussion Question 2 PEER Posts
Quantitative research has been used more often because it has a more scientific edge and rigor compared to qualitative research. Likewise, Gilad (2021), in his article is also encouraging quantitative researchers to consider the limits in their research from the lack of the qualitative piece of research, that there are advantages to mixing both methods to enrich the research. The interests of most researchers towards the qualitative method have been because off the training that they have undergone from their past professors and PhD holders who have always emphasized on Qualitative research as the most scientific method (Gilad, 2021).
Qualitative research is mostly developed out of the need to solve and issue. It is holistic working with the whole patient and family as a whole being and it is detailed and uses many ways to collect information. Nurses use this method to find ways to help patients based on their preferences. It sets the plan for future research by using quantitative or qualitative research with people experiencing and interpreting data differently based on the factors that has affected them, the truth about this research is that it is a composite of different realities (Chicca, 2020).DNP 810 Topic 4 Discussion Question 2 PEER Posts
This method still requires the researcher to follow a strict process of research by planning and finding an interesting topic, design with expansive data collection methods that will enhance the quality of the work, the researcher should bracket any personal ideas, views, biases and assumptions (Chicca, 2020).
References: DNP 810 Topic 4 Discussion Question 2 PEER Posts
Chalmers, J., & Cowdell, F. (2021). What are the quantitative and qualitative research methods? A brief introduction. Dermatological Nursing, 20(2), 45-48.
Chicca, J. (2020). Introduction to qualitative nursing research: This type of research can reveal important information that quantitative research can’t. American Nurse Journal, 15(6), 28.
Gilad, S. (2021). Mixing qualitative and quantitative methods in pursuit of Richer answers to real-world questions. Public Performance & Management Review, 44(5), 1075-1099.
https://doi.org/10.1080/15309576.2019.1694546 DNP 810 Topic 4 Discussion Question 2 PEER Posts
Nice post, the DPI projects look mostly to quantitative research because it can provide a comparison and a specific measurable patient outcome, that can easily be obtained at a clinical facility. Take care, Dr. Etheridge
Qualitative and quantitative research are both essential to nursing science. In general, qualitative research refers to studies that cannot be quantified or expressed numerically such as qualities, opinions, or feelings (Wienclaw, 2021). Data can be collected through participant observations and interviews in qualitative research.
On the other hand, quantitative research refers to observations that are measurable, expressed numerically, and can be quantified into hard facts (Wienclaw, 2021). Data can be collected through various experiments, tests, simulations. The general goal of quantitative research is to generalize results to a larger population to explain a phenomenon with numerical data collected from a smaller group (Wienclaw, 2021).
Quantitative research articles are required for the DPI project as it provides the numerical data needed to support the changes being made. With this, the variables used in quantitative research provide numerical data that can be further analyzed and used as statistical tools for implementing change (Wienclaw, 2021). DNP 810 Topic 4 Discussion Question 2 PEER Posts
In the study by Ramer et al. (2016), a randomized controlled trial was used to determine the efficacy of utilizing a VeinViewer when inserting peripheral intravenous catheters. The study included 53 participants who were randomly divided into two groups: the Veinviewer group and the standard group. Overall, results showed that nurses who used the Veinviewer had less procedural time and fewer access complications. The study qualifies as quantitative research as it included variables that are quantifiable numerically.
References: DNP 810 Topic 4 Discussion Question 2 PEER Posts
Ramer, L., Hunt, P., Ortega, E., Knowlton, J., Briggs, R., & Hirokawa, S. (2016). Effect of intravenous (IV) assistive device (VeinViewer) on IV access attempts, procedural time, and patient and nurse satisfaction. Journal of Pediatric Oncology Nursing, 33(4), 273–281. https://doi.org/10.1177/1043454215600425
Wienclaw, R. A. (2021). Quantitative and qualitative analysis. Salem Press Encyclopedia. DNP 810 Topic 4 Discussion Question 2 PEER Posts
I find your vein finder research article and DPI project very interesting. I observe many nurses utilizing a variety of vein finder in order to establish a peripheral IV. I find vein finders quite challenging to use and prefer the original method. Is there a specific vein finder you are looking to utilize in your study? I would love to hear about your discoveries.
There are many occasions where patients arrive to our institutional ED that require IV and blood work for diagnosis and treatment. Based on Pan et.al (2019) study on vein finders, a vein finder utilizes its near infrared light to assist nurses and phlebotomist in locating the vein on the first attempt. This also prevents further pain for the patient and reduces the risk of pre-analytical error. DNP 810 Topic 4 Discussion Question 2 PEER Posts
Pan, C. T., Francisco, M. D., Yen, C. K., Wang, S. Y., & Shiue, Y. L. (2019). Vein Pattern Locating Technology for Cannulation: A Review of the Low-Cost Vein Finder Prototypes Utilizing near Infrared (NIR) Light to Improve Peripheral Subcutaneous Vein Selection for Phlebotomy. Sensors (Basel, Switzerland), 19(16), 3573. https://doi.org/10.3390/s19163573
Nice post and you are so correct in stating that quantitative research can provide the numerical data needed to support the changes being made. The DPI project requires a specific measurable patient outcome, that is most clearly seen in the quantitative research. Take care, Dr. Etheridge
Quantitative research uses variable-based models that are abstract from different cases and qualitative research favors case-based models that abstract from different characteristics. These “mixed methods” approaches treat qualitative and quantitative research as complementary, rather than opposing strategies (Creswell, 2015).
Quantitative research uses large samples, random sampling from an abstract population. Qualitative research usually uses strategy of generalization that relies on exploration of theoretically sampled cases.
Sepsis has been recognized as the leading cause of death in non-coronary ICUs. To understand the impact on sepsis and septic shock, nurses need to know the signs and keep up to date with the latest evidence-based best practices (American Association of Critical Care Nurses [AACN], 2019).
Using a sepsis bundle for early detection of severe sepsis or septic shock can result for a positive patient outcome. One study looked at the feasibility of using screening tools in an intensive care unit to determine if a patient was becoming septic. (Coleman & Jackson, 2014). DNP 810 Topic 4 Discussion Question 2 PEER Posts
Quantitative research has a vital role for my proposed DPI project because I believe that this will help improve patient outcome and decrease length of stay in the hospital. It will be completed by questionnaires, face to face interaction, all clinicians will be included and data can be collected by group sample in the unit. Pre and post data collection will be collected and evaluation at the end will reveal if it will be a success project or not. Descriptive statistics will be measured and graph will be tallied for pre and post implementation of the sepsis bundle.
External validation studies are necessary to confirm the treatment practice and early medical management for patients. Using available data in ICU can predict accurately by nurses utilizing sepsis bundle prior to clinical finding. Sepsis bundle have been reported to improve survival rate and improve patient health.
References: DNP 810 Topic 4 Discussion Question 2 PEER Posts
American Association of Critical-Care Nurses. (2019). Nurses on the front line of sepsis.
Coleman, S., & Jackson, T. (2014, April). Beating Sepsis! It’s a Sprint, NOT a Jog! Critical Care Nurse, 34(2).
Creswell J. W. (2015). A Concise Introduction to Mixed Methods Research. Los Angeles, CA: Sage.
Nice post. Just a quick reminder that you, as a student, not an employee of the institution, will be the “Project Manager” and will not have any direct contact with patients. You will educate the clinical staff to implement the intervention and the clinical site will provide you the de-identified pre and post-intervention data. Take care, Dr. Etheridge
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Thank you for reminding me. I will make sure that I won’t have any direct contact with patients. DNP 810 Topic 4 Discussion Question 2 PEER Posts
Qualitative research employs a subjective approach, it is generally expressed using words. The data collection methods involved are interviews, focus groups, literature review, ethnography.
Qualitative research is holistic in nature, the reasoning used to synthesize data in this research is inductive, and exploratory research type methods (LoBiondo-Wood, G., & Haber, J. 2018). While quantitative research employs an objective approach, expressed using graphs and numbers, The data collection methods involved are experiments, surveys, and observations expressed in numbers. Quantitative research is particularistic in nature, the reasoning used to synthesize data in this research is deductive.
The data collection methods involved are experiments, surveys, and observations expressed in numbers (WHO, 2017).
In the DPI project, quantitative research will help to improve the overall service deliveries, staff working conditions, and effectiveness of new medications being used to improve patients’ care and condition. The Quantitative research method is widely used in the healthcare field to quantify behaviors, attitudes, opinions, and other important variables from a large sample of data collection.
Quantitative Research is also used to quantify the problem by way of generating numerical data or data that can be transformed into usable statistics (Esc Anna Nery 2017).
Quantitative research data collection is well structured, and it uses data to uncover facts and patterns in particular research. Most quantitative research is conducted by an online survey, face-to-face interviews, phone interviews, polls, and systematic observations. When researchers use quantitative research, they usually do not have all the information they are looking for. DNP 810 Topic 4 Discussion Question 2 PEER Posts
They must collect all the data necessary to get the results, it has improved the overall delivery of health services, helped healthcare managers improve their facilities, and helped healthcare professionals learn more about diseases and other health-related issues. For example, quantitative research studies are needed in epidemiological investigations, in which Nursing participates, but can still explore much more.
References DNP 810 Topic 4 Discussion Question 2 PEER Posts
World Health Organization; 2017 [cited 2019 Jan 14]. Alliance for Health Policy and Systems Research. What is HPSR? Overview [Internet] Geneva: Available from: http://www.who.int/alliance-hpsr/about/hpsr/en/
Esc Anna Nery 2017: Quantitative Research in Nursing Science
https://www.researchgate.net/publication/313460506_Quantitative_Research_in_Nursing_Science DNP 810 Topic 4 Discussion Question 2 PEER Posts
LoBiondo-Wood, G., & Haber, J. (2018). Nursing research: Methods and critical appraisal for evidence-based practice (7th ed.). St. Louis, MO: Mosby Elsevier
Great post and positive information. You are correct as a DNP student/researchers it is vital to maintain quantitative information as this can provide evidence base information to staffs member participating in the researches. To support the DPI project, quantitative research is more preferred since it is focused, more objective and scientific compared to qualitative research.
This implies that researchers in quantitative studies college huge amounts of data for statistical analysis. To collect huge amounts of data, researchers should use larger samples to of representative populations which grantees validity of results (Ahmad et al., 2019). Besides, large samples have minimal selection bias hence easily applicable to establish causal relations or to predict future outcomes.
References
Ahmad, S., Wasim, S., Irfan, S., Gogoi, S., Srivastava, A., & Farheen, Z. (2019). Qualitative vs. Quantitative Research. population, 1, 2.
Thanks for an educative post. Qualitative research utilizes a subjective approach, it is generally expressed using words. However, Quantitative Research is objective in approach, using numerical data and statistics to quantify their findings. Moreover, quantitative researchers have the tendency to remain objectively separated from the subject matter. This is because quantitative research only seeks accurate measurements and data analysis to answer their research or studies.
Some studies make use of both Quantitative and Qualitative Research, giving room for the two to complement each other. Generally, quantitative data provides us with the numerical data and support needed to be successful with a DPI project. Quantitative research goes through the proper channels that can translate research results into evidence-based practice (Wienclaw, 2021).
Therefore, adopting a quantitative approach in your DPI project is a great idea that will result in quality improvement for better patient outcomes.
Wienclaw, R. A. (2021). Quantitative and qualitative analysis. Salem Press Encyclopedia. DNP 810 Topic 4 Discussion Question 2 PEER Posts
Qualitative research examines the experience of a study participant. Through the experience, participants give their meaning and perception to the researcher which is then interpreted and categorized (Rutberg & Bouikidis, 2018). Quantitative research uses numeric and statistical data to examine the result of a given intervention in an impartial way (Bloomfield & Fischer, 2019). This type of research is numerical-driven and looks for objective data and statistical significance (Rutberg & Bouikidis, 2018).
Both types of research have a place. Qualitative research is often used when an issue is not well understood or there is not a vast amount of research readily available (Rutberg & Bouikidis, 2018). Quantitative data builds on prior research that has been performed (Zaccagnini & Pechacek, 2021).
The Direct Practice Improvement project (DPI) requires quantitative data. Discovering new data is not the goal of the DPI project. Further, the project requires the student to look at current research and apply evidence-based information to practice problems.
As described above, qualitative research tends to be a building block that will eventually lead to quantitative research. Using quantitative data allows the DNP student to apply previously studied knowledge to a particular practice situation. Quantitative data can take a testable hypothesis, conduct an experiment and allow the data to be evaluated, analyzed, and replicated in future studies (McLeod, 2019).
When COVID-19 struck, healthcare changed overnight.
Suddenly, people were being admitted into the hospital with a serious respiratory illness, at times, requiring intubation, and families were not allowed to be present at the bedside. Wang et al. (2022) did a primary quantitative research study comparing standard communication updates every Monday, Wednesday, Friday, and Sunday to using a WeChat Cloud service system that allowed patients and families to communicate on a regular basis. DNP 810 Topic 4 Discussion Question 2 PEER Posts
Less delirium incidence, improved patient and family satisfaction, and a reduction in labor costs were the positive findings (Wang et al., 2022). There was not a statistical difference between the control and experimental group relating to the ICU length of stay (Wang et al., 2022). Even though the ICU length of stay was not affected, a standard communication that involves the patient, family and caregivers was well received and reduced delirium incidence which would be useful at my practice site.
References DNP 810 Topic 4 Discussion Question 2 PEER Posts
Bloomfield, J., & Fisher, M. J. (2019). Quantitative research design. Journal of the Australasian Rehabilitation Nurses’ Association (JARNA), 22(2), 27–30. https://doi-org.lopes.idm.oclc.org/10.33235/jarna.22.2.27-30
McLeod, S. (2019). What’s the difference between qualitative and quantitative research? Simple Psychology. https://www.simplypsychology.org/qualitative-quantitative.html
Rutberg, s. & Bouikidis, C. (2018). Focusing on the fundamentals: A simplistic differentiation between qualitative and quantitative research. Nephrology Nursing Journal, 45 (2), 209-213.
Wang, J., Qin, J., Tung, T., Chen, J., Zheng, N., Lu, L., & Jin, Y. (2022). Impact of the “WeChat Cloud Service” Option for Patients in an Emergent Intensive Care Unit During an Epidemic in Tai Zhou China. Frontiers in Medicine, 010.3389/fmed.2021.833942
Zaccagnini, M. E., & Pechacek, J. M. (2021). The doctor of nursing practice essentials: A new model for advanced practice nursing (4th ed.). Jones and Bartlett Learning. ISBN-13: 97811284079708
Thank you for providing an insightful post. I agree that quantitative research studies are required over qualitative research for our DPI project. Overall, quantitative data provides us with the numerical data and support needed to be successful with the DPI project. Quantitative research goes through the rigor and proper channels that translate results into hard facts (Wienclaw, 2021).
Quantitative research utilizes different techniques such as randomized-controlled trials, laboratory or field experiments, and even simulations to provide reliable evidence. As you mentioned, qualitative research tends to lead to quantitative research. Qualitative research focuses more on opinions and feelings, which is not suitable for the DPI project as it does not provide the necessary support needed for a successful implementation strategy.
I am looking forward to reading more about your DPI project topic. COVID was a difficult time for patients and family members as visitation were not allowed in most organizations. Other methods of communication such as FaceTime and Zoom played a vital role during the difficult times.
Reference: DNP 810 Topic 4 Discussion Question 2 PEER Posts
Wienclaw, R. A. (2021). Quantitative and qualitative analysis. Salem Press Encyclopedia.
Thank you for your contribution. I appreciate it. While COVID has definitely had negative effects, there are some positive innovations that have contributed to patient care.
Thank you for your post, I agree with you that quantitative research is numerical-driven and looks for objective data. Quantitative data refers to any information that can be quantified, counted, or measured, and given a numerical value. Qualitative data is descriptive in nature, expressed in terms of language rather than numerical values, for example, gender, religious preference, and socio-economic status.
Quantitative research is based on numeric data, for example, weight, height, age. Qualitative research focuses on the qualities of users-the ‘why’ behind the numbers (Cargo M, Harris J, Pantoja T, et al, 2018). It’s hard to conduct a successful data analysis without qualitative and quantitative data. They both have their advantages and disadvantages and often complement each other.
Reference DNP 810 Topic 4 Discussion Question 2 PEER Posts
Cargo M, Harris J, Pantoja T, et al, 2018. Cochrane qualitative and implementation methods group guidance series-paper 4: methods for assessing evidence on intervention implementation. J Clin Epidemiol 2018; 97:59–69. 10.1016/j.jclinepi.2017.11.028
Healthcare continues to move away from a cookie-cutter approach or a one size fits all. With the advent of the human genome, therapies and treatments are targeted to meet the individual need of the patient. Using precision medicine, genetic information, environment, and lifestyle can be considered to target treatment and improve outcomes. When given the same medication, there can be unique and individual responses. Providers need to understand this potential complication and interaction with individual genetics.
Medications with narrow therapeutic windows or side effects could cause life-threatening complications. As with other areas in healthcare, studies have not included minority races which contribute to social determinants of health and health inequities (Borrell et al., 2021). Including minority groups is imperative if precision medicine is truly going to target the uniqueness of each individual. Beyond the race or ethnicity of a person, which is socially ascribed, providers should consider genetic ancestry (Borrell et al., 2021).
This represents the person’s genetic origin which is more specific and detailed to the exact but variable makeup of the individual. This more detailed information teases out some of the variations found in large race or ethnicity groups. DNP 810 Topic 4 Discussion Question 2 PEER Posts
Certain medications impact individuals differently. For example, there are different classes of medications that are prescribed to address hypertension such as beta-blockers, calcium channel blockers, ace inhibitors, or diuretics. Hypertension can be a complex genetically acquired condition. However, genetics can impact the effectiveness of different classifications of anti-hypertensive medications. Targeting individual genotypes can produce a better response to antihypertensive medications.
However, studies researching the effectiveness of the various classes of medications are inconclusive which may be due to interethnic differences (Rysz et al., 2020). Single nucleotide polymorphisms (SNPs) are considered to play a role in the inter-individual variation that can be seen with treatment response. Just as hypertension is complex and multi-causal, genetic traits are only a part of the explanation for treatment effectiveness.
Treatment response for hypertension is multifaceted, just like the disease itself. With more research and understanding of the different alleles and SNPs involved in hypertension and the effects of the medication, treatments, especially in regard to pharmacogenetics, will be able to be targeted to the genetic picture of the patient.
References DNP 810 Topic 4 Discussion Question 2 PEER Posts
Borrell, L. N., Elhawary, J. R., Fuentes-Afflick, E., Witonsky, J., Bhakta, N., Wu, A. H. B., Bibbins-Domingo, K., Rodríguez-Santana, J. R., Lenoir, M. A., Gavin, J. R., Kittles, R. A., Zaitlen, N. A., Wilkes, D. S., Powe, N. R., Ziv, E., & Burchard, E. G. (2021). Race and Genetic Ancestry in Medicine — A Time for Reckoning with Racism. N Engl J Med, 384(5), 474-480. 10.1056/NEJMms2029562
Rysz, J., Franczyk, B., Rysz-Górzyńska, M. & Gluba-Brzózka, A. (2020). Pharmacogenomics of hypertension treatment. International Journal of Molecular Science, 21 (13), 4709. Doi: https://doi.org/10.3390/ijms21134709.