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How is Vitamin D deficiency related to Diabetes type 2

 

Vitamin D Deficiency

 

Various studies have been conducted to analyze the link between vitamin D deficiency and type 2 diabetes. According to Ozfirat and Chowdhury (2010), most of the newly diagnosed patients with type 2 diabetes have lower levels of vitamin D compared to those without the disorder. Type 2 diabetes is a chronic disease characterized by a lack of insulin, insulin resistance, and high blood sugar. Low vitamin D levels in the body are the leading cause of initial and subsequent insulin resistance in diabetes 2. Insulin resistance results from the inability of the pancreas to continue pumping out more insulin to get blood sugar into cells. The pancreas has receptors for the active vitamin D metabolite that is responsible for the production of insulin. During insulin resistance, the pancreas fails to continue pumping out more insulin to make the cells respond, resulting in higher blood sugar. Continuous resistance to insulin leads to hyperglycemia which causes pre-diabetes, obesity, and cardiovascular disease.

Vitamins play a crucial role in maintaining optimal health. However, Vitamin deficiencies such as low vitamin

D levels are present in most of the older patients. The risk of increasing insulin resistance and impaired pancreatic islet function with aging makes older people more vulnerable to chronic infections. A combination of low vitamin deficiencies, increasing insulin resistance, and impaired pancreatic islet function increases the chances of developing type 2 diabetes. Also, clinical trials have shown positive results in controlling type 2 diabetes by supplementing vitamin D to the patients (Lips et al., 2017). One of the main functions of vitamin D is to improve the sensitivity of the body to insulin. Improved sensitivity to insulin reduces blood sugar levels. The introduction of vitamin D helps maintain a normal glycemic balance by minimizing insulin resistance and is considered the cure for the condition. Hence, low Vitamin D levels contribute to the onset and development of type 2 diabetes.

References

How is Vitamin D deficiency related to  Diabetes type 2

Lips, P., Eekhoff, M., van Schoor, N., Oosterwerff, M., de Jongh, R., Krul-Poel, Y., & Simsek, S. (2017). Vitamin D and type 2 diabetes. The Journal of steroid biochemistry and molecular biology173, 280-285. https://doi.org/10.1016/j.jsbmb.2016.11.021

Ozfirat, Z., & Chowdhury, T. A. (2010). Vitamin D deficiency and type 2 diabetes. Postgraduate medical journal86(1011), 18-25. http://dx.doi.org/10.1136/pgmj.2009.078626

 

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Please read through the following information on writing a Discussion question response and participation posts.

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Important information on Writing a Discussion Question

  • Your response needs to be a minimum of 150 words (not including your list of references)
  • There needs to be at least TWO references with ONE being a peer reviewed professional journal article.
  • Include in-text citations in your response
  • Do not include quotes—instead summarize and paraphrase the information
  • Follow APA-7th edition
  • Points will be deducted if the above is not followed

Participation –replies to your classmates or instructor

  • A minimum of 6 responses per week, on at least 3 days of the week.
  • Each response needs at least ONE reference with citations—best if it is a peer reviewed journal article
  • Each response needs to be at least 75 words in length (does not include your list of references)
  • Responses need to be substantive by bringing information to the discussion or further enhance the discussion. Responses of “I agree” or “great post” does not count for the word count.
  • Follow APA 7th edition
  • Points will be deducted if the above is not followed
  • Remember to use and follow APA-7th edition for all weekly assignments, discussion questions, and participation points.
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  • Student paper example
  • Citing Sources
  • The Writing Center is a great resource