NU 606 Week 3 Discussion Problem-Based Learning Case

NU 606 Week 3 Discussion Problem-Based Learning Case

NU 606 Week 3 Discussion Problem-Based Learning Case

NU606 Advanced Pathophysiology

Week 3 Discussion

Problem-Based Learning Case

Initial Post

Using the Week 3: Discussion Choice Question, choose your topic for this week’s discussion. The topics come from Chapters 5 and 7. Chapter 6 talks about infection and you should apply what you learned from Chapter 6 to your topic as well. You may use the textbook as one reference as well as the learning materials posted within the course. However, additional references should be scholarly based and be a new source that you are introducing to your peers. Remember, you should focus on the pathophysiology of the content for your initial and peer replies as well as applying your knowledge to Advanced Practice Nursing.

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Infection refers to the growth of bacteria in our bodies. Pathogenic microorganisms penetrate body tissue causing injury which then results into infection, this causes the body to react since bacteria are invaders that are not really supposed to be in the body. Because the body is reacting to these microorganisms, that implies that they are pathogens meaning that they are disease causing germs (Hubert & VanMeter, 2018). The chain of spreading an infection requires a causative agent to carry the microorganism, then who will carry it (reservoir) who could be a person, an animal, surface. Portal of exit is how to get the reservoir infected; blood, stool, mucus membrane and then transmitted air etc. The portal of entry is usually the same as the portal of exit. Then, looking at the host, what will make them good hosts, maybe they have a low immune system, poor nutrition, what is their medical history. All these factor into the spread of the infection.

There are two types of infection: local and systemic. Local infection microorganisms are usually in one specific area of the body and the signs include pain and tenderness, erythema, purulent drainage. Systemic infections will spread to various areas of the body such as the circulatory system, respiratory system and a patient will present with signs fever, weakness, headache, fatigue. The characteristic of pyrexia will vary depending on the causative organism (Hubert & VanMeter, 2018). For signs to be considered as subjective, the patient will complain of pain, tenderness, fever headache, fatigue. Objective signs are those that erythema, purulent drainage, abnormal labs. By presenting with these signs, the body is trying to communicate the invasion of microorganisms that do not actually belong there, and treatment must be initiated to heal the body.

Cross, S., Gon, G., Morrison, E., & Graham, W. J. (2020, November 11). Figure 1. chain of transmission. ResearchGate. Retrieved September 14, 2021, from

Hubert, R. J., & VanMeter, K. (2018). Gould’s Pathophysiology for the health professions (6th ed.). Elsevier.