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NURS 550 Discussion Levels of Translational Research

NURS 550 Discussion Levels of Translational Research

NURS 550 Discussion Levels of Translational Research

There are three levels of translational research: -T1- Basic research that is used to develop a new treatment or therapy. This research is conducted in a laboratory setting and aims to understand the fundamental biology behind a disease or condition. -T2- Preclinical research that is used to test the safety and efficacy of a new treatment or therapy in animals (Fort et al., 2017). This research is conducted in a laboratory setting and helps to determine if the treatment or therapy is safe and effective for humans. And -T3- Clinical trials that are used to test the safety and efficacy of a new treatment or therapy in humans. This research is conducted with patients who have the disease or condition being studied.

The use of nursing theories is critical to patient care because of the different purposes that they serve. Nursing theories assist in informing every interaction between nurses and patients. Through defining the features of the nurse-patient interaction, these theories shape how nurses develop relationships with patients (Wei et al., 2019). The purpose of most nursing theories is to help nurses identify care needs among patients, articulate what they can do for patients and why they do it, and determine the kind of information to collect to develop care plans. Through theories, nurses can comprehend and evaluate health situations, explain and anticipate certain responses from patients and map out objectives and anticipated outcomes (Bahabadi et al., 2020). These theories also help nurses determine the interventions to deliver, best practices, and selection of productive areas for research. The implication is that nursing theories are fundamental to quality care provision as they help nurses to possess background propositions to offer the best care.

There are several ways in which translational research is different from evidence-based practice (EBP). The first has to do with the idea of “evidence.” In translational research, scientists strive to move discoveries made in the laboratory into practical applications that can be used in the real world. This means that the findings of translational research are based on sound scientific evidence. In contrast, EBP relies on a body of research that has been evaluated and found to be reliable (Parija, 2020). The goal of EBP is to use this existing body of knowledge to make informed decisions about patient care. Another difference between translational research and has to do with the time frame involved. Translational take longer time compared to EBP given the stages that has to be accomplished in the entire process.

Population health management (PHM) is the field of public health that concerns itself with the health and well-being of defined populations. It is a relatively new field, having been formally recognized only in the past few decades (Fort et al., 2017). PHM is built upon the foundation of translational research, which is the process of applying knowledge and findings from basic science research to practical applications in human health care. The goal of PHM is to improve population health by using knowledge gleaned from translational research to develop and implement interventions at the individual, community, and societal levels. Some common interventions employed by PHM practitioners include educational programs, screenings, targeted treatments, and policy changes.

References

Fort, D. G., Herr, T. M., Shaw, P. L., Gutzman, K. E., &Starren, J. B. (2017). Mapping the evolving definitions of translational research. Journal of clinical and translational science1(1), 60-66.https://www.cambridge.org/core/journals/journal-of-clinical-and-translational-science/article/mapping-the-evolving-definitions-of-translational-research/39D2FB59ECC2F0C862E49E03E2403E12

Parija, S. C. (2020). Translational Research in Nursing… Vistas Galore.https://web.archive.org/web/20201212092716id_/https://pjn.sbvjournals.com/doi/pdf/10.5005/jp-journals-10084-12165

Description:
Identify the different levels of translational research. Explain how translational research is different from evidence-based practice and discuss application to population health management.

Topic 1 Participation
Description:
NA
Topic 1: Quality Research and Theoretical Frameworks

Description
Objectives:

1. Identify the different levels of translational research.
2. Differentiate translational research from evidence-based practice.
3. Discuss the application of translational research to population health management.
4. Evaluate sources of translational research.
5. Select a valid nursing practice problem for an evidence-based practice project proposal.
Study Materials
Advanced Practice Nursing: Essential Knowledge for the Profession
Description:
Read Chapters 22 and 23 in Advanced Practice Nursing: Essential Knowledge for the Profession.
Evidence-Based Practice in Nursing and Healthcare
Description:
Read Chapter 1 in Evidence-Based Practice in Nursing and Healthcare.
World Health Organization (WHO)
Description:
Explore the World Health Organization (WHO) website.
Centers for Disease Control and Prevention (CDC)
Description:
Explore the Centers for Disease Control and Prevention (CDC) website.
State and County Departments of HealthNURS 550 Discussion Levels of Translational Research
Description:
Explore the websites of your state and county departments of health and access mortality and morbidity data. The link to the Arizona Department of Health Services website is provided, but students living in other states should access their county and state departments.
Non-Communicable Diseases (NCD) Burden of Disease
Description:
Read “Non-Communicable Diseases (NCD) Burden of Disease,” by the U.S. Department of Health and Human Services, located on the Centers for Disease Control and Prevention website.

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GCU Library: Nursing and Health Sciences Research Guide
Description:
Review the “Nursing and Health Sciences” research guide, located on the GCU Library website.
The Electronic Health Record: A Friend or Foe of Translational Research and Evidence-Based Practice?
Description:
Read “The Electronic Health Record: A Friend or Foe of Translational Research and Evidence-Based Practice?” by Chipps et al., from Worldviews on Evidence-Based Nursing (2019).
Evidence-Based Practice
Description:
Read “Evidence-Based Practice” by Melnyk and Fineout-Overholt, from Encyclopedia of Nursing Research (2017).
Translation Research in Practice: An Introduction
Description:
Read “Translation Research in Practice: An Introduction,” by Titler, from Online Journal of Issues in Nursing (2018).
On Biostatistics and Clinical Trials: PICO, PICOTS, PICOTT Framework for Clinical Questions as a Way to Design Clinical Trials
Description:
Read “PICO, PICOTS, PICOTT Framework for Clinical Questions as a Way to Design Clinical Trials,” by Deng, from
On Biostatistics and Clinical Trials (2020).
Course Description
In this course learners examine the process of scientific inquiry, knowledge generation, utilization, and dissemination of evidence into advanced nursing practice in order to propose quality-improvement initiatives that advance the delivery of safe, high-quality care for patient populations. Learners critically evaluate evidence, including scientific findings from the biopsychosocial fields, epidemiology, biostatistics, genetics, and genomics, and apply levels of evidence and theoretical frameworks to design culturally appropriate clinical prevention interventions and population-based care that reduces risks, prevents disease, and promotes health and well-being. Learners also consider strategies to evaluate health policy and advocacy issues, the state of health care delivery, patient-centered care, and ethical principles related to health beliefs, health promotion, and risk reduction for diverse populations. Learners apply these strategies to work towards recognizing gaps in nursing and health care knowledge, identifying potential solutions or innovations for those gaps, planning and implementing practice changes, and evaluating the outcomes in order to improve practice. Prerequisite: NUR-513.
Pre-Requisites
NUR-513.
Co-Requisites
None
NUR-550
Course Materials

Description:
Nash, D. B., Fabius, R. J., Skoufalos, A., Clarke, J. L., & Horowitz, M. R. (2019). Population health: Creating a culture of wellness (3rd ed.). Jones & Bartlett Learning. ISBN-13: 9781284047929
Evidence-Based Practice in Nursing and Healthcare : A Guide to Best Practice
Description:
Melnyk, B. M., & Fineout-Overholt, E. (2019). Evidence-based practice in nursing and healthcare: A guide to best practice (4th ed.). Wolters Kluwer. ISBN-13: 9781496384539
APA Writing Style
Description:
APA Style is required for all writing assignments in this course, where indicated. Please prepare these assignments according to the APA Style Guide, located in the in the Student Success Center.
You may want to consider purchasing a copy of the APA style guide, as this will be a useful resource throughout your program
The Writing Process Access
Description:
View “The Writing Process” media presentation for information on how to strengthen your writing for future assignments.
University Policy Handbook
Description:
Read the Code of Conduct and Academic Standards section of the University Policy Handbook.
Library Walk Through Tutorial
Description:
View the “Library Walk Through Tutorial.”
Academic Integrity
Description:
Read the “About LopesWrite” and “Plagiarism” sections of the Academic Integrity page of the GCU website.
GCU Library: General Research Guide
Description:
Review the “General Research” guide, located on the GCU Library website.
GCU Library: Persistent Links
Description:
Review “Persistent Links,” located on the GCU Library website, to learn how to locate persistent links for library articles, videos, etc.
RefWorks and EndNote: RefWorks and EndNote Login
Description:
Manage your citations with the RefWorks tool, located on the GCU Library website. RefWorks automates the creation of your reference lists in the format of your choice (APA, MLA, etc.).
GCU Library Research Guides: Citing Sources
Description:
Reference the “GCU Library Research Guides: Citing Sources” resource for information on how to cite sources properly.
Writing Center
Description:
Refer to the resources located in the Writing Center for PowerPoint guidelines, APA style, writing and library tutorials, and research and writing assistance.
Statement on the Integration of Faith and Work
Description:
“Grand Canyon University prepares learners to become global citizens, critical thinkers, effective communicators, and responsible leaders by providing an academically-challenging, values-based curriculum from the context of our Christian heritage” (GCU Mission Statement). Review the “Statement on the Integration of Faith and Work” to become familiar with many fundamental Christian worldviews and consider how they may apply in the context of this course.